The complete MK677 guide: Benefits, dosage and cycles

If you’re searching for a way to improve your muscle growth, sleep quality, and recovery, MK677, also known as Ibutamoren, might be the solution you’re seeking. This powerful compound has gained popularity in the bodybuilding and fitness communities for its numerous benefits.

In this comprehensive guide, we will dive into MK677, focusing on the essential aspects of MK677 dosage and cycle to help you make informed decisions and achieve the best results.

What is MK677?

MK677 is a non-peptide agonist of the ghrelin receptor and a growth hormone secretagogue. It stimulates the release of growth hormone (GH) and insulin-like growth factor 1 (IGF-1) by mimicking the action of the hormone ghrelin.

Because MK677 is orally active, it is a convenient and far less expensive alternative to growth hormone injections. Despite being commonly grouped with selective androgen receptor modulators (SARMs), MK677 is not a SARM.

What does MK-677 do to your body?

MK677 works by binding to the ghrelin receptor, which is found in various tissues throughout the body, including the brain, pituitary gland, and stomach. Once bound, MK677 triggers the release of growth hormone from the pituitary gland, leading to increased levels of GH and IGF-1 in the bloodstream. The rise in these hormones promotes muscle growth, fat metabolism, and numerous other health benefits.

Benefits of MK677

MK-677 offers a range of benefits that can appeal to athletes, bodybuilders, and anyone looking to improve their overall health and well-being. From promoting muscle growth and fat loss to enhancing sleep quality and supporting bone health, MK-677 has the potential to be a powerful addition to your supplement regimen.

Muscle Growth and recovery

One of the most well-known benefits of MK-677 is its ability to promote muscle growth by increasing levels of GH and IGF-1 in the body. These hormones play a crucial role in muscle protein synthesis and overall muscle development.

As a result, MK-677 can help individuals build lean muscle mass and improve their overall physique. In addition, the increased GH and IGF-1 levels can accelerate muscle recovery, allowing for more intense and frequent training sessions.

Fat loss

MK-677 can aid in fat loss by improving the body’s energy metabolism. The increased levels of GH can promote lipolysis, the process by which stored fat is broken down and used for energy. This can lead to a reduction in body fat and an improvement in overall body composition.

Furthermore, MK-677 has been shown to improve insulin sensitivity, which can enhance the body’s ability to utilize glucose for energy and prevent fat storage.

Improved Sleep quality

MK-677 has been reported to improve sleep quality, specifically deep, restorative sleep, which is essential for optimal recovery, hormone production, and overall health.

Adequate sleep is vital for muscle growth and repair, cognitive function, and immune system support. By promoting better sleep quality, MK-677 can contribute to improved physical and mental well-being.

Bone health

Another benefit of MK-677 is its potential to improve bone health by increasing bone mineral density and promoting bone turnover.

The increased levels of GH and IGF-1 can stimulate bone formation and resorption, leading to stronger, healthier bones. This can be particularly beneficial for athletes and older individuals who are at risk of developing osteoporosis and other bone-related disorders.

MK-677 Dosage and cycle length

To fully enjoy the benefits of MK677, it’s crucial to understand the recommended dosage, cycle length, and the best time to take it.

The key to get the most benefits from this compound, is to take a moderate dose for an extended period of time. While growth hormone levels stay pretty stable during a cycle, the levels of IGF-1 will increase more the longer you take it.

If you are willing to take MK 677 in cycles for the duration of 16 to 20 weeks, the advised dosage is 25mg, and no more than that. You can also take a 5 week break and continue with your MK 677 cycle again. You will surely get good results by following the same cycle pattern of this compound.

Recommended Dosage

The optimal MK677 dosage for most individuals is between 10 and 50mg per day. For most users 25mg seems to be the sweet spot, providing optimal benefits with minimal side effects.

Beginners should start with a lower dosage (10 mg) and monitor their response before increasing the dose. Keep in mind that higher dosages may lead to increased side effects.

Cycle Length

An MK677 cycle typically lasts between 8 and 12 weeks, followed by a break of at least 4 weeks. This break allows your body to recover and helps prevent any potential negative effects associated with long-term use. However, as we mentioned, it is not uncommon to take a cycle of 16 to 20 weeks.

Best Time to Take MK677

MK677 can be taken once daily due to its long half-life (approximately 24 hours). Some users prefer to take it at night, as it may cause drowsiness and improve sleep quality. However, it can also be taken in the morning or split into two doses (morning and evening) if desired.

Dosage used in clinical trials

During a clinical trial participants where given 25mg per day for a period of 2 years. One of the conclusion of the trial was:

“Daily administration of MK-677 significantly increased growth hormone and insulin-like growth factor I levels to those of healthy young adults without serious adverse effects. Over 12 months, the ghrelin mimetic MK-677 enhanced pulsatile growth hormone secretion, significantly increased fat-free mass, and was generally well tolerated. Long-term functional and, ultimately, pharmacoeconomic, studies in elderly persons are indicated.“

source: https://pubmed.ncbi.nlm.nih.gov/18981485/

Potential Side Effects

While MK677 is generally considered safe, some potential side effects may occur, especially at higher dosages.

Common Side Effects

1. Increased appetite
2. Water retention (bloating)
3. Mild muscle and joint pain
4. Lethargy and drowsiness

Rare Side Effects

1. Elevated blood sugar levels
2. Insulin resistance
3. Numbness and tingling in extremities

Please keep in mind that we are talking about a research chemical here. What this means is that the MK-677 long-term side effects are unknown at this moment.

MK677 results

Week 1 and 2 Before and After

Within the first 2 weeks of the usage of MK 677, it will make you gain weight instead of dropping down. Performing the 2 weeks cycle can make you gain around 2 to 4 pounds. However, this can happen mostly, if you are only focusing on workout plan and not showing any consideration about diet plan.

In order to get good and beneficial outcomes by MK 677, you should involve low-carb diet in your dietary plan which helps in melting the subcutaneous fat and kicks your muscle gains. In addition, you will find the boosted energy levels and improvement in sleeping cycle with no complains about muscle fatigue.

Mk677 results before and after Week 3 and 4

In the next two weeks of MK 677 cycle, the real results will begin to show up. You will start noticing the drop down in weight, but the one thing that will increase will be your hunger.

If you are following proper workout plan, you will achieve great fat burning results and will notice some great benefits on your overall health. Your skin, hair and nail will get better and you will definitely see some inches lost from your waist line.

Mk 677 Before and After Week 5 and 6

In this phase, your body will enter into a challenging zone where you will start noticing weight gain. However, that gain will be due to lean muscle mass. Your abdominal and belly fat will be significantly gone and it will be an overall healthy change in your body. By the 6^th week, you will notice that your power to kill the workouts in gym will be intensified and your body will be more defined and better cuts.

Stacking MK677

While MK-677 can be effective on its own, many individuals choose to stack it with other compounds to enhance its benefits and achieve specific fitness goals.

Stacking MK-677 with RAD-140 and LGD-4033

One of the most common stacks includes MK-677 combined with LGD-4033 (Ligandrol) and RAD-140 (Testolone). This combination can lead to accelerated muscle growth, increased strength, and improved recovery.

SARMs target androgen receptors in muscle and bone tissue, promoting anabolic effects without the negative side effects of anabolic steroids. When stacked with MK-677, the increased GH and IGF-1 levels further enhance the anabolic environment, leading to more significant gains.

	Week 1	Week 2	Week 3	Week 4	Week 5	Week 6	Week 7	Week 8
Ibutamoren	25mg	25mg	25mg	25mg	25mg	25mg	25mg	25mg
Testolone	10mg	10mg	10mg	10mg	10mg	10mg	10mg	10mg
Ligandrol	10mg	10mg	10mg	10mg	10mg	10mg	10mg	10mg

Stacking MK-677 with Cardarine

Another popular stack involves combining MK-677 with Cardarine (GW-501516), a PPARδ agonist that has been shown to improve endurance and promote fat loss. This combination can help users achieve a lean, muscular physique while also improving cardiovascular performance.

Cardarine works by increasing the body’s utilization of stored fat for energy, while MK-677 promotes muscle growth and recovery. Together, they can create a powerful synergy for enhanced body composition and athletic performance.

	Week 1	Week 2	Week 3	Week 4	Week 5	Week 6	Week 7	Week 8
Ibutamoren	25mg	25mg	25mg	25mg	25mg	25mg	25mg	25mg
Cardarine	20mg	20mg	20mg	20mg	20mg	20mg	20mg	20mg

Read our article about the top 5 best SARM stacks for more information

Ibutamoren FAQ